Pureblome™: the new ingredient from Provital powered by Triplobiome™ Technology

Provital creates Pureblome™ by isolating the highly bioactive endophytic bacterium, Bacillus velezensis, from within the leaf tissue of the agro-ecologically cultivated hyssop (Hyssopus officinalis) from Parc de les Olors

27 of March of 2025
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Pureblome™ Provital
Pureblome™ Provital

In recent years, the conversation around femininity has shifted, intertwining ideas of empowerment, timeless beauty, and self-actualization. Today, from ages 30 to 50, women are embracing a new phase of thriving. They are now blooming in health, beauty, and vigor, and their beauty demands are increasively selective of those products targeting their specific needs. Among these, adult acne is especially booming in the well-aging scene.

In the current circumstances for adult women, a holistic blend of the psychological balance and physical renewal that the new science of Ecopsychology offers, along with the certainty and mental comfort of sustainable production practices like Agroecology, enable women to find both grounding and growth. This is the essence of Pureblome™, a new ecosystem ingredient powered by Triplobiome™ Technology.

By harnessing the profound relationships between plants and their internal symbiotic microorganisms (endophytes), Triplobiome™ creates a unique synergy that embraces the interkingdom relations within the whole ecosystem. By leveraging this innovative endophyte-based biotechnology, Provital creates Pureblome™ when isolating the highly bioactive endophytic bacterium Bacillus velezensis from the inside of the leaf tissue of the agroecologically grown hyssop (Hyssopus officinalis), sourced from Parc de les Olors; thus creating the first Agro-psychological solution to really tap into nature’s wisdom to achieve balance and rejuvenation.

To better understand the synergistic efficacy of the active metabolites produced through this interkingdom symbiosis, a Metabolomic Analysis was conducted on the B. velezensis ferment later used to create Pureblome™, where a wide range of peptides, lipopeptides, and other anti-pathogenic molecules from the plant’s world were identified.

This new ecosystem ingredient - standardized in peptides - harnesses the vast metabolic potential of nature to adress the broad challenges of mature women with a triple efficacy approach that combines anti-acne and well-aging benefits.

Backed by advanced in vitro and in vivo research, Pureblome™ promotes overall skin regeneration through a dual action targeting specific cell types:

  • By boosting fibroblast revitalization, Pureblome™ stimulates collagen and elastin production and decreases glycation, hence addresseing the root causes of skin aging and structural integrity.
  • By regulating sebocyte activity, balancing sebum production and reducing acne-related factors, Pureblome™ restores skin balance and promotes a healthy, radiant skin.
  • By a comprehensive anti-inflammatory effect proven by cytokine activity reduction, it promotes an even skin tone while counteracting the effects of inflammaging.

Further proven by clinical expert analysis and instrumental measurements on 76 female volunteers, Pureblome™ demonstrated statistically significant results vs placebo just after 14 days in the reduction of pore size, blemish number, wrinkle depth, as well as in the increased skin elasticity, skin tone evenness and overall balanced complexion. Plus, after 56 days, even better results were achieved for all these parameters, plus for sebum reduction, improvement in mattified complexion, reduction in pathogenic microbial markers (Porphyrins IX), and epidermal renewal.

With such a multi-dimensional efficacy, Pureblome™ appears as a 100% natural origin (ISO16128), COSMOS-approved ecosystem ingredient that, thanks to its symbiotic origin, delivers nature’s balance, resilience, and regenerative power directly to the skin.